Physically Hacking Windows Computers via FireWire
This is impressive:
With Winlockpwn, the attacker connects a Linux machine to the Firewire port on the victim’s machine. The attacker then gets full read-and-write memory access and the tool deactivates Windows’s password protection that resides in local memory. Then he or she has carte blanche to steal passwords or drop rootkits and keyloggers onto the machine.
Full disk encryption seems like the only defense here.